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پس از وقوع یک پدیده سوپرمون (ابرماه) اسرارآمیز، یک ژن نهفته در انسانها فعال شده که باعث میشود هر کسی در معرض نور ماه قرار بگیرد به گرگینه تبدیل شده و افراد زیادی را به قتل برساند. حال با گذشت یک سال از این حادثه، دو دانشمند تلاش میکنند جلوی تبدیل شدن انسانها به گرگینههای وحشی را بگیرند، اما A year after a supermoon’s light activated a dormant gene, transforming humans into bloodthirsty werewolves and causing nearly a billion deaths, the nightmare resurfaces as the supermoon rises again. Two scientists attempt to stop the mutation but fail, leaving those exposed to the moonlight to once again become feral werewolves. Chaos engulfs the streets as the scientists struggle to reach one of their family homes, now under siege by the savage creatures.